Lorenzo's Oil

Nick Nolte

Augusto Odone

Susan Sarandon

Michaela Odone

Peter Ustinov

Professor Nikolais

Ann Hearn

Loretta Muscatine

Maduka Steady

Omuori

Aaron Jackson

Francesco Odone

Laura Linney

Young Teacher

Kathleen Wilhoite

Deirdre Murphy

Gerry Bamman

Doctor Judalon

Margo Martindale

Wendy Gimble

James Rebhorn

Ellard Muscatine

Colin Ward

Jake Gimble

LaTanya Richardson Jackson

Nurse Ruth

Jennifer Dundas

Nurse Nancy Jo

William Cameron

Pellerman

Becky Ann Baker

Pellerman's Secretary

Mary Pat Gleason

The Librarian

David Shiner

Clown