Katie Stuart

Meg Murry

Gregory Smith

Calvin O'Keefe

David Dorfman

Charles Wallace Murry

Chris Potter

Dr. Jack Murry

Kyle Secor

The Man With Red Eyes

Sean Cullen

Happy Medium

Sarah-Jane Redmond

Dr. Dana Murry

Kate Nelligan

Mrs. Which

Alison Elliott

Mrs. Who

Alfre Woodard

Mrs. Whatsit

Munro Chambers

Sandy Murry

Noel Fisher

16 Year Old "IT" Boy

Anita Adams

Billy's Mom