Annihilation

Natalie Portman

Lena

Jennifer Jason Leigh

Dr Ventress

Gina Rodriguez

Anya Thorensen

Tessa Thompson

Josie Radek

Tuva Novotny

Cass Sheppard

Oscar Isaac

Kane

Benedict Wong

Lomax

Sonoya Mizuno

Humanoid / Katie (Med Student)

David Gyasi

Daniel

John Schwab

Paramedic

Sammy Hayman

Mayer

Josh Danford

Shelley

Kristen McGarrity

Lena Double

Kumud Pant

Scientist

Honey Holmes

Scientist (uncredited)

Hiten Patel

Scientist (uncredited)

Kola Bokinni

Peyton (uncredited)

Cosmo Jarvis

Special Ops Soldier (uncredited)