Ryan Reynolds
Wade Wilson / Deadpool / Juggernaut (voice)
Pemeran
Josh Brolin
Cable
Morena Baccarin
Vanessa
Julian Dennison
Firefist
Zazie Beetz
Domino
T.J. Miller
Weasel
Leslie Uggams
Blind Al
Karan Soni
Dopinder
Brianna Hildebrand
Negasonic Teenage Warhead
Jack Kesy
Black Tom
Eddie Marsan
Headmaster
忽那汐里
Yukio
Stefan Kapičić
Colossus (voice)
Randal Reeder
Buck
Nikolai Witschl
Head Orderly Frye
Thayr Harris
Sergei Valishnikov
Rob Delaney
Peter
Lewis Tan
Shatterstar
