Tobey Maguire
Spider-Man / Peter Parker
Pemeran
Willem Dafoe
Green Goblin / Norman Osborn
Kirsten Dunst
Mary Jane Watson
James Franco
Harry Osborn
Cliff Robertson
Ben Parker
Rosemary Harris
May Parker
J.K. Simmons
J. Jonah Jameson
Joe Manganiello
Flash Thompson
Gerry Becker
Maximilian Fargas
Bill Nunn
Joseph 'Robbie' Robertson
Jack Betts
Henry Balkan
Stanley Anderson
General Slocum
Ron Perkins
Dr. Mendel Stromm
Michael Papajohn
Carjacker
K.K. Dodds
Simkins
Ted Raimi
Hoffman
Bruce Campbell
Ring Announcer
Elizabeth Banks
Miss Brant
