Frank Welker
George / Duck / Cow (voice)
George, O Curioso 2: Siga Aquele Macaco!
George conhece Kayla, uma filhote de elefante, numa apresentação de circo. George decide ajudá-la a reencontrar sua família e para isso precisará cruzar o país.
Elenco
Amy Hill
Flower Pot Lady / Irate Woman (voice)
Ed O'Ross
Ivan the Doorman (voice)
Carlos Alazraqui
Newspaper Vendor / Conductor (voice)
Jeff Bennett
Ted (voice)
Fred Tatasciore
Mr. Bloomsberry (voice)
Nickie Bryar
Maggie / Teenage Boy (voice)
Jamie Kennedy
"Danno" Wolfe (voice)
Catherine Taber
Tina (voice)
Tim Curry
Piccadilly (voice)
Jeff McNeal
Kayla / Hog / Tonga / Layla (voice)
Cree Summer
Ms. Fisher / Cargo Pilot (voice)
Matt Lauer
Hark Hanson (voice)
Melissa Greenspan
Phone Operator (voice)
Jerry Lewis
Stationmaster (voice)
Clint Howard
Farmer Dan (voice)
Trupti Potdukhe
Anna (voice)
Phil LaMarr
Animal Park Attendant (voice)
